We partner with open innovation pioneer InnoCentive® to crowd-source solutions to our R&D challenges. Challenge descriptions and prizes are posted on the InnoCentive portal.

In order to expand our problem solving ecosystem, we are openly sharing key R&D challenges and looking for ways to collaborate with anyone willing to offer innovative solutions. Our challenges span many therapeutic areas and disciplines.

Our therapy areas:

  • Cardiovascular, renal and metabolism
  • Oncology
  • Respiratory, Inflammation and Autoimmunity
  • Neuroscience

Our disciplines:

  • Biology
  • Chemistry
  • Statistics and clinical sciences.


How Challenges work

We partner with open innovation pioneer InnoCentive® to crowd-source solutions to our R&D challenges. Challenge descriptions and prizes posted on the InnoCentive portal.


Current Challenges

We are currently preparing new challenges. Please check back soon


Completed Challenges

  • Improving Protein Expression and Optimising Protein Purification (AWARD: $25,000 | under evaluation)
  • Effective Oral Delivery of High Molecular Weight Compounds (AWARD: $25,000 | under evaluation)
  • Digital Health Solutions for Clinical Trial Acceleration or Improved Clinical Outcomes (AWARD: varies | under evaluation)
  • In Vitro System to Assess Gastrointestinal Toxicity (AWARD: $25,000 USD  | under evaluation)
  • Robust Online In Vivo Measurement of Biomarker Concentrations (AWARD: $25,000 USD  | under evaluation)
  • Automating drug administration and removal in multiwell plates (AWARD: varies | under evaluation)
  • In vitro proximal tubule model systems (US$15,000 award granted)
  • In vitro models of glomerular function (US$15,000 award granted)
  • Retrievable device for islet transplantation (US$25,000 award granted)
  • Developing clinically-relevant models for DLBCL (US$25,000 award granted)
  • Quantitative measure of covalent binding (AWARD: US$25,000 | under evaluation)
  • A sticky problem – modeling tablet stickiness (US$10,000 award granted)
  • Pressure-sensing core for cardiac microtissues  (2 x US$12,500 awards granted)
  • Developing a minimally invasive glucose monitor    (eRFP | under evaluation)
  • Novel biomarkers for neuropathic pain  (US$25,000  not awarded)
  • Targeted delivery of oligonucleotides (2 x US$10,000 awards granted)
  • Novel disease indications for AZ clinical compounds ( 2 x US$10,000 awards granted)
  • Enhancing Therapeutic Delivery with Cell-Penetrating Peptides (AWARD: varies | DEADLINE: March 16, 2018)
  • Novel Approaches to Form and Particle Control a Crystalline Material (AWARD: varies | DEADLINE: April 16, 2018)
  • AstraZeneca Challenge: Molecular Strategies to Minimize Off-Target Toxicities of Antibody Drug Conjugates (AWARD: $15,000 USD  |  DEADLINE: Sep 30 2019 23:59 EDT)
  • AstraZeneca Challenge: Improving the Targeting and Transduction Efficiency of Adeno-Associated Viral Vectors (AWARD: $25,000 USD  |  DEADLINE: Oct 15 2019 23:59 EDT)
  • AstraZeneca Challenge: Automated Detection and Quantitation of Bone Marrow Cells (AWARD: $25,000 USD  |  DEADLINE: Jan 03 2020 23:59 EST)

The AstraZeneca Open Innovation Pavilion displays all public AstraZeneca challenges.  For more information, contact InnoCentive online, or call 1-855-CROWDNOW (276-9366).