Clinical Compound Bank
Access our patient-ready compounds with evidence of human target coverage and manageable tolerability.
Access compounds with optimised pharmacological properties for preclinical research to study pathways and mechanisms of disease biology.
Have a novel target idea or assay for a drug discovery project? Our diverse High Throughput Screening (HTS) compound library may help you advance or validate your idea.
New Molecule Profiling
Explore the properties and therapeutic potential of your novel compounds by leveraging our cheminformatic and screening technologies.
Offer and be rewarded for your innovative ideas and research expertise to help overcome difficult R&D barriers.
Do you have an idea, technology or suggestion outside of these categories? We are still welcoming proposals, so please get in touch.
Leading the Way in Open Innovation
clinical and preclinical projects in progress
compounds available from our screening library
R&D Challenges awarded to date
Why collaborate through Open Innovation?
Beyond the usual research partnerships – let's push the boundaries of science together
AstraZeneca has spent decades creating unique enabling tools and technologies of interest to the scientific community of investigators. These include optimised compounds with extensive data packages, high throughput screening libraries and facilities, cheminformatics and other in silico analytics, and drug R&D knowhow, expertise and experience. At the same time, academic, research foundation and biotech investigators have been developing insights, tools, technologies, platforms, resources and facilities that complement those of AstraZeneca. Examples include disease pathophysiology and patient care insights, assay, biomarker and imaging technologies, and specialised facilities.
By bringing all of this together through partnering, we can test hypotheses that may otherwise not be possible. Sharing ideas and enabling scientific innovation to cross boundaries between academia, industry, government and non-profit organisations will help us translate innovative ideas into scientific breakthroughs and potential new medicines more quickly and effectively.
At AstraZeneca, we have great scientists doing truly ground-breaking research. But in order to speed up the delivery of the next generation of medicines, we also need to access the best science outside our labs. We are always looking for new ways of working with academic or industry researchers who share our passion for advancing the science and helping patients with unmet medical needs.
In 2011, a novel agreement between the Medical Research Council (MRC) and AstraZeneca gave academic researchers across the UK unprecedented access to 22 of our clinical and preclinical compounds.
These compounds had stalled in early testing, often because they didn’t prove effective against the original target. But they may still be useful against other diseases. And because the compounds have already undergone some preliminary development, any new treatments arising from the research could reach patients faster. Fifteen studies are currently underway covering respiratory illness, muscular dystrophies, bone disease and various mental health conditions.
Latest Partnering news
FDA accepts for review New Drug Application for sodium zirconium cyclosilicate (ZS-9) for the treatment of hyperkalaemia
AstraZeneca featured news
My lung cancer journey
LabTalk blog post by Dr Denny Clifford - “Early in my career as a practicing Pulmonary and Critical Care specialist I was fortunate to be a Principal Investigator on an AstraZeneca study, which led to a long relationship investigating new pharmaceuticals in the Respiratory field. In my 33 years as a practicing doctor I have diagnosed over 800 lung cancers, and dedicated my time to providing patients with the best possible care.”
Lung Cancer Awareness Month: Spreading the Word about Scientific Advances
November is Lung Cancer Awareness Month; an important occasion when we can pause to reflect on valuable diagnostic and treatment advances in our journey to improving cancer outcomes. These scientific discovery milestones continue to excite me, along with the wider scientific community, and provide hope to patients and their loved ones.
Harnessing personalised healthcare to identify novel therapeutic targets for Chronic Kidney Disease (CKD) patients
Each November, more than 13,000 leading nephrologists and other medical and scientific professionals from around the world present and discuss the latest advances and challenges in kidney research and treatment at the American Society of Nephrology Kidney Week. This year, with a steadily growing presence, AstraZeneca is presenting five abstracts from our early science research teams alone that unveil new evidence for novel, potential chronic kidney disease (CKD) drug targets that leverage our personalised healthcare approach.